diff --git a/docs/python_build.rst b/docs/python_build.rst
index 4bc4fcd..b89c788 100644
--- a/docs/python_build.rst
+++ b/docs/python_build.rst
@@ -278,20 +278,14 @@
 Python build supports creating wheels for individual packages and groups of
 packages. Building the ``.wheel`` subtarget creates a ``.whl`` file for the
 package using the PyPA's `build <https://pypa-build.readthedocs.io/en/stable/>`_
-tool. The location of this file is recorded with `GN metadata
+tool.
+
+The ``.wheel`` subtarget of ``pw_python_package`` records the location of
+the generated wheel with `GN metadata
 <https://gn.googlesource.com/gn/+/master/docs/reference.md#var_metadata>`_.
-
-The ``pw_python_wheels`` template creates a collection of wheels from a list of
-``pw_python_package`` targets and their dependencies. It uses GN metadata to
-locate the wheels for all transitive dependencies. This collection can be used
-to deploy packages to different Python environments without requiring the
-original source repository.
-
-.. admonition:: Under construction
-
-  Pigweed's wheel building is not yet fully implemented. ``pw_python_wheels``
-  currently only supports listing individual ``setup.py`` files. This will be
-  updated to automatically collect wheels for all transitive dependencies.
+Wheels for a Python package and its transitive dependencies can be collected
+from the ``pw_python_package_wheels`` key. See
+:ref:`module-pw_build-python-wheels`.
 
 Protocol buffers
 ^^^^^^^^^^^^^^^^
diff --git a/pw_build/BUILD.gn b/pw_build/BUILD.gn
index c9399fb..7c4be4a 100644
--- a/pw_build/BUILD.gn
+++ b/pw_build/BUILD.gn
@@ -132,6 +132,7 @@
 # Requirements for the pw_python_package lint targets.
 pw_python_requirements("python_lint") {
   requirements = [
+    "build",
     "mypy==0.800",
     "pylint==2.6.0",
   ]
diff --git a/pw_build/python.gni b/pw_build/python.gni
index d04d027..2b1ce22 100644
--- a/pw_build/python.gni
+++ b/pw_build/python.gni
@@ -1,4 +1,4 @@
-# Copyright 2020 The Pigweed Authors
+# Copyright 2021 The Pigweed Authors
 #
 # Licensed under the Apache License, Version 2.0 (the "License"); you may not
 # use this file except in compliance with the License. You may obtain a copy of
@@ -38,13 +38,11 @@
 #     - $name.lint.pylint - Runs pylint (if enabled).
 #   - $name.tests - Runs all tests for this package.
 #   - $name.install - Installs the package in a venv.
-#   - $name.wheel - Builds a Python wheel for the package. (Not implemented.)
+#   - $name.wheel - Builds a Python wheel for the package.
 #
 # All Python packages are instantiated with the default toolchain, regardless of
 # the current toolchain.
 #
-# TODO(pwbug/239): Implement wheel building.
-#
 # Args:
 #   setup: List of setup file paths (setup.py or pyproject.toml & setup.cfg),
 #       which must all be in the same directory.
@@ -68,6 +66,7 @@
 #       provided, mypy's default configuration file search is used. mypy is
 #       executed from the package's setup directory, so mypy.ini files in that
 #       directory will take precedence over others.
+#
 template("pw_python_package") {
   # The Python targets are always instantiated in the default toolchain. Use
   # fully qualified labels so that the toolchain is not lost.
@@ -340,18 +339,27 @@
         }
       }
 
-      # TODO(pwbug/239): Add support for building groups of wheels. The code below
-      #     is incomplete and untested.
+      # Builds a Python wheel for this package. Records the output directory
+      # in the pw_python_package_wheels metadata key.
       pw_python_action("$target_name.wheel") {
-        script = "$dir_pw_build/py/pw_build/python_wheels.py"
+        metadata = {
+          pw_python_package_wheels = [ "$target_out_dir/$target_name" ]
+        }
+
+        module = "build"
 
         args = [
-          "--out_dir",
-          rebase_path(target_out_dir),
-        ]
-        args += rebase_path(_all_py_files)
+                 rebase_path(_setup_dir),
+                 "--wheel",
+                 "--no-isolation",
+                 "--outdir",
+               ] + rebase_path(metadata.pw_python_package_wheels)
 
-        deps = [ ":${invoker.target_name}.install" ]
+        deps = [ ":${invoker.target_name}" ]
+        foreach(dep, _python_deps) {
+          deps += [ string_replace(dep, "(", ".wheel(") ]
+        }
+
         stamp = true
       }
     } else {
@@ -467,6 +475,9 @@
           inputs = [ invoker.mypy_ini ]
         }
       }
+
+      # Generated packages with linting disabled never need the whole file list.
+      not_needed([ "_all_py_files" ])
     }
   } else {
     # Create groups with the public target names ($target_name, $target_name.lint,
diff --git a/pw_build/python.rst b/pw_build/python.rst
index 7157746..520b333 100644
--- a/pw_build/python.rst
+++ b/pw_build/python.rst
@@ -75,6 +75,30 @@
     pylintrc = "$dir_pigweed/.pylintrc"
   }
 
+
+.. _module-pw_build-python-wheels:
+
+Collecting Python wheels for distribution
+-----------------------------------------
+The ``.wheel`` subtarget generates a wheel (``.whl``) for the Python package.
+Wheels for a package and its transitive dependencies can be collected by
+traversing the ``pw_python_package_wheels`` `GN metadata
+<https://gn.googlesource.com/gn/+/master/docs/reference.md#var_metadata>`_ key,
+which lists the output directory for each wheel.
+
+The ``pw_mirror_tree`` template can be used to collect wheels in an output
+directory:
+
+.. code-block::
+
+  import("$dir_pw_build/mirror_tree.gni")
+
+  pw_mirror_tree("my_wheels") {
+    path_data_keys = [ "pw_python_package_wheels" ]
+    deps = [ ":python_packages" ]
+    directory = "$root_out_dir/the_wheels"
+  }
+
 pw_python_script
 ================
 A ``pw_python_script`` represents a set of standalone Python scripts and/or
@@ -88,13 +112,6 @@
 These targets do not add any files. Their subtargets simply forward to those of
 their dependencies.
 
-pw_python_wheels
-================
-Builds and collects Python wheels for one or more ``pw_python_package`` targets.
-A package's ``.wheel`` subtarget builds the wheel for just that package.
-``pw_python_package`` collects wheels from all of its transitive dependencies
-and collects them in a specified directory.
-
 pw_python_requirements
 ======================
 Represents a set of local and PyPI requirements, with no associated source